Larger-scale Study Indicates a Survival Benefit From Radiation Therapy in High-grade Soft Sarcomas
May 3, 2010
Overall survival increased in a population study of 6,960 patients with high-grade soft sarcomas treated with radiation therapy, reported Matthew Koshy, M.D., Shayna E. Rich, MA, and Majid M. Mohiuddin, M.D., in a May 1, 2010, article.
The overall three-year survival was 73 percent for the 47 percent of patients who received radiation therapy versus 63 percent for those patients who did not, the authors found. They reviewed the Surveillance, Epidemiology and End Results (SEER) database from Jan. 1, 1988, to Dec. 31, 2005, to assess the overall survival curves for patients with low- and high-grade tumors. Based on a multivariate analysis, patients with low-grade tumors did not show any improvement in survival.
Only 13.5 percent of the patients who received radiation therapy did so in a neoadjuvant setting.
The article, “Improved Survival With Radiation Therapy in High-Grade Soft
Tissue Sarcomas of the Extremities: A SEER Analysis,” was published in the May 1, 2010, International Journal of Radiation Oncology Biology·Physics.
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